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Index > Protein center > LDLR(Gene name) > Pig
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  • LDLR (Gene name),
  • Low-density lipoprotein receptor (Protein name ),  LDLR_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LDLR;
    Protein name:
    Low-density lipoprotein receptor(LDL receptor);
    Alternative:

    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Interacts with LDLRAP1. Interacts with SNX17. Interacts with ARRB1.
    Function:
    Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Endomembrane system Single-pass type I membrane protein Membrane clathrin-coated pit Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    811
    Sequence:
    50:
    FQCQDGKCIS | YKWICDGNTE | CKDGSDESLE | TCMSVTCKIG | DFSCGGRVNR | 
    100:
    CIPESWRCDG | QQDCENGSDE | EGCSPKTCSQ | DEFRCQDGKC | IAPKFVCDSD | 
    150:
    RDCLDGSDEA | SCPTPTCGPA | SFQCNSSTCI | PELWACDGDP | DCEDGSDEWP | 
    200:
    QHCRSHSSSL | PERSNNPCSA | LEFHCHSGEC | IHSSWRCDGD | TDCKDKSDEE | 
    250:
    NCDVATCRPD | EFQCSDGTCI | HGSRQCDREY | DCKDMSDEQG | CVNATLCEGP | 
    300:
    NKFKCQSGEC | ISLDKVCNSV | RDCRDWSDEP | LKECGTNECL | DNKGGCSHIC | 
    350:
    NDLKIGYECL | CPEGFQLVDK | HRCEDIDECQ | DPDACSQICV | NLEGSYKCQC | 
    400:
    EEGFQLEPLT | KACKAIGTIA | YLFFTNRHEV | RKMTLDRSEY | TSLIPNLKNV | 
    450:
    VALDTEVASN | RIYWSDLSQR | KIYSTQIDRA | PSFSSYDTII | GEDLQAPDGL | 
    500:
    AVDWIHSNIY | WTDSILGTVS | VADTKGVKRK | TLFQEKGSKP | RAIVVDPVHG | 
    550:
    FMYWTDWGTP | AKIKKGGLNG | VDVYSLVTED | IQWPNGITLD | LSGGRLYWVD | 
    600:
    SKLHSISSID | VNGGNRKTVL | EDKTKLAHPF | SLAIFEDKVF | WTDIINEAIF | 
    650:
    SANRLTGSDI | HLMAENLLSP | EDIVLFHNLT | QPRGVNWCER | TALQNGGCQY | 
    700:
    LCLPAPQINP | RSPKFTCACP | DGMLLAKDMR | SCLTETEPAG | TTQGPSMVNS | 
    750:
    TAVGPKHTAS | SELTTAESVT | MSQHALGDVA | GRGVTEKPQS | VGALYIVLPI | 
    800:
    ALLILLFFGT | FLLWKNWRLK | SINSINFDNP | VYQKTTEDEV | HICRSQDGYT | 
    811:
    YPSRQMVSLE | D
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Pig LDL receptor
    Cat.:
    E1008r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig LDL receptor
    Cat.:
    E1008m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig LDL receptor
    MSDS:
    Please sign in first.
    ELISA Kit for Pig LDL receptor
    Cat.:
    E1008h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig LDL receptor
    Cat.:
    E1008p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig LDL receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Pig LDL receptor
    Cat.:
    U1008r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig LDL receptor
    Cat.:
    U1008p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig LDL receptor
    Cat.:
    U1008m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig LDL receptor
    Cat.:
    U1008h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig LDL receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Pig LDL receptor
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Pig LDL receptor
    Cat.:
    P1008Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig LDL receptor
    Polyclonal Antibody for Pig LDL receptor
    Polyclonal Antibody for Pig LDL receptor
    Polyclonal Antibody for Pig LDL receptor
    Cat.:
    P1008Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig LDL receptor
    Cat.:
    P1008Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig LDL receptor
    Monoclonal Antibody for Pig LDL receptor
    Monoclonal Antibody for Pig LDL receptor
    Monoclonal Antibody for Pig LDL receptor
    Monoclonal Antibody for Pig LDL receptor
    Monoclonal Antibody for Pig LDL receptor
    Protein for Pig LDL receptor
    Protein for Pig LDL receptor
    Protein for Pig LDL receptor
    Protein for Pig LDL receptor
    Protein for Pig LDL receptor
    Protein for Pig LDL receptor

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    References
    1. 1.
      "Identification of a mutation in the low density lipoprotein receptor gene associated with recessive familial hypercholesterolemia in swine."
      Hasler-Rapacz J. , Ellegren H. , Fridolfsson A.-K. , Kirkpatrick B. , Kirk S. , Andersson L. , Rapacz J.
      Am. J. Med. Genet.76:379-386(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-801;VARIANT FH CYS-84
      tissue: Liver.
    2. 2.
      "Identification of a novel Arg-->Cys mutation in the LDL receptor that contributes to spontaneous hypercholesterolemia in pigs."
      Grunwald K.A.A. , Schueler K. , Uelmen P.J. , Lipton B.A. , Kaiser M. , Buhman K. , Attie A.D.
      J. Lipid Res.40:475-485(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 20-801;VARIANT FH CYS-84
      tissue: Skin fibroblast.
    3. 3.
      "Mechanisms of regulation of ovarian sterol metabolism by insulin-like growth factor type II: in vitro studies with swine granulosa cells."
      Garmey J.C. , Day R.N. , Day K.H. , Veldhuis J.D.
      Endocrinology133:800-808(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 765-811
      tissue: Corpus luteum.
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